Whether you're connecting with the Real Tone Cable, the Rocksmith+ Connect app, or your own ASIO or WASAPI device, this Connectivity and Troubleshooting Guide is here to help: RS+ConnectivityGuide.pdf
Rocksmith+ recommends setting your PCs audio input and output sample rate to 16-bit, 48000 Hz (DVD Quality) – here's how: W10SampleRateInstructions.pdf